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Colorectal cancer

What is the role of lymph node metastases in the progression of colorectal cancer?

The presence of lymph node metastases (LNM) is considered one of the most important features of colorectal cancer (CRC) staging, indicating the need for additional surgery after local excision and adjuvant chemotherapy after surgery. Now, a new study challenges the role of LNM in the progression of CRC.

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Figure 1: The spread of colorectal cancer metastases.

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Correspondence to Iris D. Nagtegaal or Hans-Joachim Schmoll.

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Nagtegaal, I., Schmoll, HJ. What is the role of lymph node metastases in the progression of colorectal cancer?. Nat Rev Gastroenterol Hepatol 14, 633–634 (2017). https://doi.org/10.1038/nrgastro.2017.122

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